Recombinant Human Arylsulfatase A/ARSA Protein (His Tag)
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- 表达系统： HEK293 Cells
- 蛋白编码： AAH14210.2
| 别称 |
Arylsulfatase A;ASA;Cerebroside-Sulfatase;ARSA
|
| 表达系统 |
HEK293 Cells
|
| 序列 |
Arg19-Ala507
|
| 蛋白编码 |
AAH14210.2
|
| 种属 |
Human
|
| 计算分子量 |
52.9 kDa
|
| 表观分子量 |
50-65 kDa
|
| 标签 |
C-His
|
| 纯度 |
> 95 % as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
|
| 保存条件 |
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
|
| 运输条件 |
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
|
| 制剂 |
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 300mM NaCl, pH 8.0.
|
| 复溶方法 |
Not Applicable
|
| 背景 |
Arylsulfatase A (ARSA) is a lysosomal enzyme that breaks down Cerebroside 3-Sulfate, a major constituent of the myelin sheet, into Cerebroside and Sulfate. The ARSA deficiency results in Metachromatic Leukodystrophy (MLD), a lysosomal storage disease in the central and peripheral nervous systems with severe and progressive neurological symptoms. Recombinant Human ARSA corresponds to the ARSA mature peptide and has sulfatase activity.
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实验操作视频
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