Recombinant Human Carbonic Anhydrase 4/CA4 Protein (His Tag)
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- 表达系统： E.coli
- 蛋白编码： P22748
| 别称 |
Carbonic Anhydrase 4;Carbonate Dehydratase IV;Carbonic Anhydrase IV;CA-IV;CA4;CAIV;Car4;RP17
|
| 表达系统 |
E.coli
|
| 序列 |
Ala19-Lys283
|
| 蛋白编码 |
P22748
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| 种属 |
Human
|
| 计算分子量 |
31.4 kDa
|
| 表观分子量 |
30 kDa
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| 标签 |
C-His
|
| 纯度 |
> 95 % as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
|
| 保存条件 |
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
|
| 运输条件 |
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
|
| 制剂 |
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, pH 8.5.
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| 复溶方法 |
Not Applicable
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| 背景 |
Carbonic Anhydrase 4 (CA4) belongs to the alpha-carbonic anhydrase family. Alpha-carbonic anhydrase is a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. Carbonic anhydrase 4 is a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and certain other) capillaries and proximal renal tubules. Carbonic anhydrase 4 may stimulate the sodium/bicarbonate transporter activity of SLC4A4 that acts in pH homeostasis. It may have a role in inherited renal abnormalities of bicarbonate transport. Furthermore, Carbonic anhydrase 4 is essential for acid overload removal from the retina and retina epithelium and acid release in the choriocapillaris.
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实验操作视频
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