Recombinant Human Carbonic Anhydrase 8/CA8 Protein (His Tag)
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- 表达系统： E.coli
- 蛋白编码： P35219
| 别称 |
Carbonic Anhydrase-Related Protein;CARP;Carbonic Anhydrase VIII;CA-VIII;CA8;CALS;CAMRQ3;MGC120502;MGC99509
|
| 表达系统 |
E.coli
|
| 序列 |
Ala2-Gln290
|
| 蛋白编码 |
P35219
|
| 种属 |
Human
|
| 计算分子量 |
34.0 kDa
|
| 表观分子量 |
40 kDa
|
| 标签 |
C-His
|
| 纯度 |
> 95 % as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
|
| 保存条件 |
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
|
| 运输条件 |
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
|
| 制剂 |
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 500mM NaCl, 1mM DTT, pH 8.5.
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| 复溶方法 |
Not Applicable
|
| 背景 |
Carbonic Anhydrase 8 (CA8) belongs to the alpha-carbonic anhydrase family. Alpha-carbonic anhydrase is a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. Because CA8 has some sequence similarity with other known carbonic anhydrase genes, it was firstly called as CA-related protein. Nevertheless, CA8 does not have a carbonic anhydrase catalytic activity. Defects in CA8 are the cause of cerebellar ataxia mental retardation and dysequilibrium syndrome type 3 (CMARQ3), which is a congenital cerebellar ataxia associated with dysarthia, quadrupedal gait and mild mental retardation.
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实验操作视频
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