Recombinant Human Cathepsin D/CTSD Protein (His Tag)
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- 表达系统: HEK293 Cells
- 蛋白编码: P07339
别称 |
Cathepsin D;CTSD;CLN10;CPSD;HEL-S-130P
|
表达系统 |
HEK293 Cells
|
序列 |
Leu21-Leu412
|
蛋白编码 |
P07339
|
种属 |
Human
|
计算分子量 |
43.6 kDa
|
表观分子量 |
50 kDa
|
标签 |
C-His
|
纯度 |
> 95 % as determined by reducing SDS-PAGE.
|
内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
|
保存条件 |
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
|
运输条件 |
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
|
制剂 |
Supplied as a 0.2 μm filtered solution of 20mM MES, 150mM NaCl, pH 5.5.
|
复溶方法 |
Not Applicable
|
背景 |
The protein acid protease active in intracellular protein breakdown and involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease. It is specificity similar to; but narrower than; that of pepsin A and it does not cleave the 4-Gln-|-His-5 bond in B chain of insulin. It consists of a light chain and a heavy chain and expressed in the aorta extrcellular space. The Val-58 allele is significantly overrepresented in demented patients (11.8%) compared with non-demented controls (4.9%). Carriers of the Val-58 allele have a 3.1-fold increased risk for developing AD than non-carriers.It belongs to the peptidase A1 family
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实验操作视频
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