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Recombinant Human CD155/PVR/NECL5 Protein (His Tag)

Price: ¥4200 ¥2200

Size:
50μg 10μg
  • 表达系统: HEK293 Cells
  • 蛋白编码: NP_006496
  • 应用性: BLI
别称
Poliovirus Receptor;Nectin-Like Protein 5;NECL-5;CD155;PVR;PVS
表达系统
HEK293 Cells
序列
Trp21-Asn343
蛋白编码
NP_006496
种属
Human
计算分子量
36.1 kDa
表观分子量
58 kDa
标签
C-His
生物活性
Loaded Human TIGIT-Fc on Protein A Biosensor, can bind Human PVR-His with an affinity constant of 4.22 nM as determined in BLI assay.
纯度
> 95 % as determined by reducing SDS-PAGE.
内毒素
< 1.0 EU per μg of the protein as determined by the LAL method.
保存条件
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
运输条件
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
制剂
Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
复溶方法
Not Applicable
背景
Poliovirus Receptor (PVR) is a 70 kDa type I transmembrane single-span glycoprotein that belongs to the nectin-like (Necl) family and was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV); an etiologic agent of the central nervous system disease poliomyelitis. PVR contains three Ig-like extracellular domains; a transmembrane segment; and a cytoplasmic tail. The normal cellular function of PVR maybe the involvement of intercellular adhension between epithelial cells. Alternate splicing of the PVR mRNA yields four different isoforms (α; β; γ; and δ) with identical extracellular domains.


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