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Recombinant Human Chitotriosidase/CHIT1 Protein (His Tag)

Price: ¥5328 ¥1784

Size:
50μg 10μg
  • 表达系统: HEK293 Cells
  • 蛋白编码: AAI03696.1
别称
Chitotriosidase-1;Chitinase-1;CHIT1;CHI3;CHIT;CHITD
表达系统
HEK293 Cells
序列
Ala22-Asn466
蛋白编码
AAI03696.1
种属
Human
计算分子量
50.4 kDa
表观分子量
54 kDa
标签
C-His
纯度
> 95 % as determined by reducing SDS-PAGE.
内毒素
< 1.0 EU per μg of the protein as determined by the LAL method.
保存条件
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
运输条件
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
制剂
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 7.5.
复溶方法
Not Applicable
背景
Chitotriosidase-1 (CHIT1) is a glycoprotein that belongs to the Glycosyl Hydrolase 18 family and Chitinase class II subfamily. It is secreted by cultured macrophages and serves to degrade chitin, chitotriose and chitobiose. CHIT1 may participate in the defense against nematodes and other pathogens. It is highly expressed in the plasma of patients with Gaucher's disease type I, which can be used as diagnostic aid and to evaluate the success of treatment that brings levels back to normal. The amino acid sequence of human CHIT1 is 99%, 76%, 75% and 55% identical to that of chimpanzee, rat, mouse and fruit fly, respectively.


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