Recombinant Human Fas Ligand / TNFSF6 (N-6His)
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- 表达系统： HEK293 Cells
- 蛋白编码： P48023
| 别称 |
apoptosis (APO-1) antigen ligand 1;Apoptosis antigen ligand;APT1LG1CD95L;APTL;CD178 antigen;CD178;CD95L;CD95-L;Fas antigen ligand;Fas ligand (TNF superfamily;member 6);Fas Ligand;FASLCD95 ligand;FASLG;TNFSF6
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| 表达系统 |
HEK293 Cells
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| 序列 |
Pro134-Leu281
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| 蛋白编码 |
P48023
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| 种属 |
Human
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| 计算分子量 |
17.7 kDa
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| 表观分子量 |
20-30 kDa
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| 标签 |
N-His
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| 纯度 |
> 95 % as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
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| 保存条件 |
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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| 运输条件 |
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
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| 制剂 |
Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
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| 复溶方法 |
Not Applicable
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| 背景 |
Fas ligand is also known as FasL, CD178, CD95L, or TNFSF6, is a homotrimeric type-II transmembrane protein that belongs to the tumor necrosis factor (TNF) family. Its ability to induce apoptosis in target cells plays an important role in the development, homeostasis, and function of the immune system. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.
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实验操作视频
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