Recombinant Human GALNT3 Protein (His Tag)
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- 表达系统： HEK293 Cells
- 蛋白编码： Q14435
| 别称 |
Polypeptide N-acetylgalactosaminyltransferase 3;Polypeptide GalNAc transferase 3;GalNAc-T3;pp-GaNTase 3;Protein-UDP acetylgalactosaminyltransferase 3;UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3;HFTC;HHS
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| 表达系统 |
HEK293 Cells
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| 序列 |
Gln38-Asp633
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| 蛋白编码 |
Q14435
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| 种属 |
Human
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| 计算分子量 |
69.1 kDa
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| 表观分子量 |
80 kDa
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| 标签 |
C-His
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| 纯度 |
> 85 % as determined by reducing SDS-PAGE.
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| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
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| 保存条件 |
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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| 运输条件 |
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
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| 制剂 |
Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
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| 复溶方法 |
Not Applicable
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| 背景 |
Polypeptide N-acetylgalactosaminyltransferase 3(GALNT3) belongs to the glycosyltransferase 2 family and galNAc-T subfamily. It expressed in organs that contain secretory epithelial glands and it highly expressed in pancreas, skin, kidney and testis. There are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also called GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal binding .This protein plays a major role in regulating phosphate levels within the body (phosphate homeostasis). Among its many functions, phosphate plays a critical role in the formation and growth of bones in childhood and helps maintain bone strength in adults.
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实验操作视频
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