Recombinant Human GITRL protein(His tag)
Price:
- 表达系统: HEK293 Cells
- 蛋白编码: Q9UNG2
别称 |
Activation-inducible TNF-related ligand;AITRL;Glucocorticoid-induced TNF-related ligand;hGITRL
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表达系统 |
HEK293 Cells
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序列 |
Leu49-Ser177
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蛋白编码 |
Q9UNG2
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种属 |
Human
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计算分子量 |
14.6 kDa
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表观分子量 |
15 kDa
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标签 |
C-His
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纯度 |
> 90 % as determined by reducing SDS-PAGE.
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内毒素 |
Please contact us for more information.
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保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
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运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
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制剂 |
Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
复溶方法 |
Please refer to the printed manual for detailed information.
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背景 |
Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B. Triggers increased phosphorylation of STAT1 and up-regulates expression of VCAM1 and ICAM1.Promotes leukocyte adhesion to endothelial cells .Regulates migration of monocytes from the splenic reservoir to sites of inflammation.
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实验操作视频
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