Recombinant Human Glucagon/GCG Protein (His Tag)
Price:
- 表达系统： HEK293 Cells
- 蛋白编码： P01275
| 别称 |
Glucagon;Glicentin;Glicentin-Related Polypeptide;GRPP;Oxyntomodulin;OXM;OXY;Glucagon;Glucagon-Like Peptide 1;GLP-1;Incretin Hormone;Glucagon-like Peptide 1;GLP-1;Glucagon-Like Peptide 2;GLP-2;GCG
|
| 表达系统 |
HEK293 Cells
|
| 序列 |
Arg21-Lys180
|
| 蛋白编码 |
P01275
|
| 种属 |
Human
|
| 计算分子量 |
18.6 kDa
|
| 表观分子量 |
19 kDa
|
| 标签 |
C-His
|
| 纯度 |
> 95 % as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
|
| 保存条件 |
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
|
| 运输条件 |
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
|
| 制剂 |
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 200mM NaCl, 1mM DTT, 50% Glycerol, pH 8.0.
|
| 复溶方法 |
Not Applicable
|
| 背景 |
Glucagon is a secreted protein and belongs to the glucagon family. Glucagon can be cleved into 8 chains, playing an important role in initiating and maintaining hyperglycemic conditions in diabetes. Glucagon can regulates blood glucose by decreasing glycolysis and increasing gluconeogenesis. In addition, Glucagon is involved in initiating and maintaining hyperglycemic conditions in diabetes. Glucagon release is stimulated by hypoglycemia and inhibited by hyperglycemia, insulin, and somatostatin. In the glucagon antagonist, His-53 and Phe-58 are missing. This antagonist has been successfully utilized to reduce glucose concentration in vivo.
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实验操作视频
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