Recombinant Human JAM-B/CD322 Protein (Fc Tag)
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- 表达系统： HEK293 Cells
- 蛋白编码： P57087
| 别称 |
Junctional Adhesion Molecule B;JAM-B;Junctional Adhesion Molecule 2;JAM-2;Vascular Endothelial Junction-Associated Molecule;VE-JAM;CD322;JAM2;C21orf43;VEJAM
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| 表达系统 |
HEK293 Cells
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| 序列 |
Phe29-Asn236
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| 蛋白编码 |
P57087
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| 种属 |
Human
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| 计算分子量 |
50.4 kDa
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| 表观分子量 |
60-75 kDa
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| 标签 |
C-Fc
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| 纯度 |
> 95 % as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
|
| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
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| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
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| 制剂 |
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| 复溶方法 |
Please refer to the printed manual for detailed information.
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| 背景 |
Junctional Adhesion Molecule B (JAM-B) is a single-pass type I membrane protein that belongs to the juctional adhesion molecules family. JAM-B includes a signal sequence (aa 1-28); an extracellular region (aa 29-238) with one Ig-like C2-type domain and one Ig-like V-type domain; a transmembrane segment (aa 239-259); and a cytoplasmic domain (aa 260 - 298). JAMB is localized to the tight junctions between endothelial cells or epithelial cells. JAM-B is prominently expressed in the heart; placenta; lung; foreskin and lymph node. It is also present on the endothelia of other vessels. JAM-B acts as an adhesive ligand for interacting with a variety of immune cell types and may play a role in lymphocyte homing to secondary lymphoid organs.
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实验操作视频
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