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Recombinant Human Peroxiredoxin 5/PRDX5 Protein (His Tag)

Price: ¥2376 ¥936

Size:
50μg 10μg
  • 表达系统: HEK293 Cells
  • 蛋白编码: P30044
别称
Peroxiredoxin-5;PRDX5;Alu corepressor 1;Antioxidant enzyme B166;AOEB166;Liver tissue 2D-page spot 71B;PLP;Peroxiredoxin V;Prx-V;Peroxisomal antioxidant enzyme;TPx type VI;Thioredoxin peroxidase PMP20;Thioredoxin reductase
表达系统
HEK293 Cells
序列
Met53-Leu214
蛋白编码
P30044
种属
Human
计算分子量
17.9 kDa
表观分子量
17 kDa
标签
N-His
纯度
> 95 % as determined by reducing SDS-PAGE.
内毒素
< 1.0 EU per μg of the protein as determined by the LAL method.
保存条件
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
运输条件
This product is provided as lyophilized powder which is shipped with ice packs.
制剂
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
复溶方法
Please refer to the printed manual for detailed information.
背景
Peroxisomes are essential organelles that participate in multiple important metabolic processes, including the β-oxidation of fatty acids, plasmalogen synthesis, and the metabolism of reactive oxygen species (ROS). Peroxiredoxins is overexpressed in breast cancer tissues to a great extent suggesting that they has a proliferative effect and may be related to cancer development or progression. Peroxiredoxin 5 (PRDX5) is a thioredoxin peroxidase that belongs to the atypical 2-Cys class of the TSA/ahpC family of peroxiredoxins. PRDX5 is a widely expressed mitochondrial antioxidant enzyme that reduces hydrogen peroxide, alkyl hydroperoxides, and peroxynitrite. In human cells, this enzyme is present in the cytosol, mitochondria, peroxisomes, and nucleus.


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