Recombinant Human TCblR/8D6A Protein (Fc Tag)
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- 表达系统： HEK293 Cells
- 蛋白编码： Q9NPF0
| 别称 |
CD320 antigen;8D6 antigen;FDC-signaling molecule 8D6;FDC-SM-8D6;Transcobalamin receptor;TCblR;CD320
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| 表达系统 |
HEK293 Cells
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| 序列 |
Ser36-Val231
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| 蛋白编码 |
Q9NPF0
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| 种属 |
Human
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| 计算分子量 |
47.3 kDa
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| 表观分子量 |
58-60 kDa
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| 标签 |
C-Fc
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| 纯度 |
> 85 % as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
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| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
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| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
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| 制剂 |
Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| 复溶方法 |
Please refer to the printed manual for detailed information.
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| 背景 |
CD320 antigen is also known as 8D6 antigen,FDC-signaling molecule 8D6,Transcobalamin receptor and 8D6A. It is a single-pass type I membrane protein and containing two LDL-receptor class A domains. CD320 has been recently discovered and reported as a follicular dendritic cell (FDC) protein. CD320 can augments the proliferation of plasma cells precursors generated by IL-10. CD320 also founctions a receptor for the cellular uptake of transcobalamin bound cobalamin. Defects in CD320 are the cause of methylmalonic aciduria type TCblR (MMATC) which is a metabolic disorder.
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实验操作视频
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