Recombinant Rhesus Macaque Tumor-associated Calcium Signal Transducer 2/TROP-2 (C-6His)
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- 表达系统： HEK293 Cells
- 蛋白编码： XP_001114599.1
- 应用性： BLI
| 别称 |
Tumor-associated calcium signal transducer 2;Membrane component chromosome 1 surfacemarker 1;Cell surface glycoprotein Trop-2;TACSTD2;TROP2
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| 表达系统 |
HEK293 Cells
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| 序列 |
His27-Arg272
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| 蛋白编码 |
XP_001114599.1
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| 种属 |
Rhesus Macaque
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| 计算分子量 |
28.7 kDa
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| 表观分子量 |
38-45 kDa
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| 标签 |
C-His
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| 生物活性 |
Loaded Anti-Human TROP-2 mAb-Fc on Protein A Biosensor, can bind Rhesus Macaque TROP-2-His with an affinity constant of 0.29 nM as determined in BLI assay.
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| 纯度 |
> 95 % as determined by reducing SDS-PAGE.
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| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
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| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
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| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
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| 制剂 |
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| 复溶方法 |
Please refer to the printed manual for detailed information.
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| 背景 |
Tumor associated calcium signal transducer 2 (TACSTD2, TROP-2) is a type I cell surface glycoprotein that is highly expressed on human carcinomas. It was originally identified as an antigen present on human gastrointestinal tumors and is the second of two members of this family. Human and mouse TROP-2 share 87% amino acid (aa) similarity. TROP-2 is capable of transducing an intracellular calcium signal and may play a role in tumor growth. It also has adhesive functions.
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实验操作视频
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