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RITA1 Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human esophagus cancer
Dilution
IHC 1:50-1:200
Clonality
Polyclonal
Isotype
IgG
Immunogen
Fusion protein of human RITA1
Abbre
RITA1
Synonyms
C12orf52 ;Chromosome 12 open reading frame 52 ;RBPJ interacting and tubulin associated 1;RBPJ interacting and tubulin associated protein 1;RBPJ-interacting and tubulin-associated protein;RITA;RITA抗体
Swissprot
Cellular Localization
Cytoplasm. Nucleus. Cytoplasm>cytoskeleton>centrosome. Shuttles rapidly between the cytoplasm and the nucleus. The function of centrosome localization is still unclear.
Concentration
1.02 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method
Antigen affinity purification
Research Areas
Developmental biology; Neuroscience; Signal transduction; Stem cells
Conjugation
Unconjugated
Background
Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis.
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using RITA1 Polyclonal Antibody at dilution of 1:60(×200)


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