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RNASE1 Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human; Mouse; Rat
  • 应用性: WB;IHC
Verified Samples
Verified Samples in WB:Rat pancreas,Mouse pancreas
Verified Samples in IHC:Human cervical cancer
Dilution
WB 1:500-1:2000;IHC 1:50-1:100
Clonality
Polyclonal
Isotype
IgG
Immunogen
Fusion protein of human RNASE1
Abbre
RNASE1
Synonyms
HP-RNase;Pancreatic ribonuclease;Rib 1;RIB-1;Rib1;Ribonuclease 1;Ribonuclease A;Ribonuclease a family 1;Ribonuclease pancreatic;Ribonuclease RNase A family 1;Ribonuclease RNase A family 1 pancreatic;RNAS1_HUMAN;RNase 1;RNase A;RNase UpI-1;Rnase1;RNAseA抗体
Swissprot
Calculated MW
18 kDa
Observed MW
Refer to figures
Cellular Localization
Extracellular region or secreted
Concentration
0.9 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method
Antigen affinity purification
Research Areas
Epigenetics and Nuclear Signaling
Conjugation
Unconjugated
Background
This gene encodes a member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. The encoded endonuclease cleaves internal phosphodiester RNA bonds on the 3'-side of pyrimidine bases. It prefers poly(C) as a substrate and hydrolyzes 2',3'-cyclic nucleotides, with a pH optimum near 8.0. The encoded protein is monomeric and more commonly acts to degrade ds-RNA over ss-RNA. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.
Western blot analysis of Rat pancreas tissue and Mouse pancreas tissue lysates using RNASE1 Polyclonal Antibody at dilution of 1:650
Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using RNASE1 Polyclonal Antibody at dilution of 1:50(×200)


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