SCCPDH Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主： Rabbit
- 反应性： Human; Mouse; Rat
- 应用性： WB;IHC
| Verified Samples |
Verified Samples in WB:Human fetal liver,PC-3,A172 Verified Samples in IHC:Human tonsil,Human esophagus cancer |
| Dilution | WB 1:1000-1:5000;IHC 1:50-1:300 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Fusion protein of human SCCPDH |
| Abbre | SCCPDH |
| Synonyms | CGI 49;CGI49;FLJ43187;Probable saccharopine dehydrogenase;Saccharopine dehydrogenase;SCCPDH;SCPDH |
| Swissprot | |
| Calculated MW | 47 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Extracellular region or secreted,extracellular region,Mitochondrion,Nucleus,Other locations:lipid droplet,membrane,midbody,platelet alpha granule lumen |
| Concentration | 1.5 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Purification Method | Antigen affinity purification |
| Research Areas | Metabolism; Signal Transduction |
| Conjugation | Unconjugated |
| Background | SCCPDH (Probable saccharopine dehydrogenase) is a 429 amino acid protein that belongs to the saccharopine dehydrogenase family. The SCCPDH gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, fruit fly, mosquito and C.elegans, and maps to human chromosome 1q44. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. |
Western blot analysis of Human fetal liver tissue PC-3 and A172 cell lysates using SCCPDH Polyclonal Antibody at dilution of 1:1000
Immunohistochemistry of paraffin-embedded Human tonsil tissue using SCCPDH Polyclonal Antibody at dilution of 1:85(×200)
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using SCCPDH Polyclonal Antibody at dilution of 1:85(×200)
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