SCN11A Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主： Rabbit
- 反应性： Human;Mouse;Rat
- 应用性： IHC
| Verified Samples |
Verified Samples in IHC:Human breast cancer,Human ovarian cancer |
| Dilution | IHC 1:50-1:200 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Synthetic peptide of human SCN11A |
| Abbre | SCN11A |
| Synonyms | hNaN;NaN;NAV1.9;Peripheral nerve sodium channel 5;PN 5;PN5;SCN 11A;SCN 12A;Scn11a;SCN12A;SCNBA;Sensory neuron sodium channel 2;SNS 2;SNS2;Sodium channel protein type 11 subunit alpha;Sodium channel protein type XI subunit alpha;Sodium channel voltage gated type XI alpha;Sodium channel voltage gated type XI alpha polypeptide;Sodium channel voltage gated type XI alpha subunit;Sodium channel voltage gated type XII alpha polypeptide;Voltage gated sodium channel Nav1.9;Voltage gated sodium channel subunit alpha Nav1.9;Voltage-gated sodium channel subunit alpha Nav1.9 |
| Swissprot | |
| Cellular Localization | Membrane. |
| Concentration | 0.3 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Purification Method | Affinity purification |
| Research Areas | Neuroscience |
| Conjugation | Unconjugated |
| Background | Voltage-gated sodium channels are membrane protein complexes that play a fundamental role in the rising phase of the action potential in most excitable cells. Alpha subunits, such as SCN11A, mediate voltage-dependent gating and conductance, while auxiliary beta subunits regulate the kinetic properties of the channel and facilitate membrane localization of the complex. Aberrant expression patterns or mutations of alpha subunits underlie a number of disorders. Each alpha subunit consists of 4 domains connected by 3 intracellular loops; each domain consists of 6 transmembrane segments and intra- and extracellular linkers. |
Immunohistochemistry of paraffin-embedded Human breast cancer tissue using SCN11A Polyclonal Antibody at dilution 1:50
Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using SCN11A Polyclonal Antibody at dilution 1:50
| E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
| E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
| E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
