SNCA Polyclonal Antibody
Price:
Size:
100μL
50μL
- 宿主: Rabbit
- 反应性: Human;mouse;Rat
- 应用性: WB
Verified Samples |
Verified Samples in WB:SH-SY5Y,Mouse brain,Rat brain |
Dilution | WB 1:500-1:1000 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Recombinant Human SNCA protein expressed by E.coli |
Abbre | SNCA |
Synonyms | SNCA;NACP; PARK1;Non-A beta component of AD amyloid;Non-A4 component of amyloid precursor |
Swissprot | |
Calculated MW | 14 kDa |
Observed MW | 16 kDa |
Concentration | 1 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH 7.4 |
Purification Method | Affinity purification |
Research Areas | Cancer; Neuroscience |
Conjugation | Unconjugated |
Background | Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release.Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores.Mechanistically, acts by increasing local Ca2+ release from microdomains which is essential for the enhancement of ATP-induced exocytosis.Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs at presynaptic plasma membrane in conjunction with cysteine string protein-alpha/DNAJC5. |
Western blot with SNCA Polyclonal antibody at dilution of 1:500.lane 1:SH-SY5Y whole cell lysate, lane 2:Mouse brain, lane 3:Rat brain
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