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SNCA Polyclonal Antibody

Price: ¥1640 ¥1010

Size:
100μL 50μL
  • 宿主: Rabbit
  • 反应性: Human;mouse;Rat
  • 应用性: WB
Verified Samples
Verified Samples in WB:SH-SY5Y,Mouse brain,Rat brain
Dilution
WB 1:500-1:1000
Clonality
Polyclonal
Isotype
IgG
Immunogen
Recombinant Human SNCA protein expressed by E.coli
Abbre
SNCA
Synonyms
SNCA;NACP; PARK1;Non-A beta component of AD amyloid;Non-A4 component of amyloid precursor
Swissprot
Calculated MW
14 kDa
Observed MW
16 kDa
Concentration
1 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH 7.4
Purification Method
Affinity purification
Research Areas
Cancer; Neuroscience
Conjugation
Unconjugated
Background
Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release.Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores.Mechanistically, acts by increasing local Ca2+ release from microdomains which is essential for the enhancement of ATP-induced exocytosis.Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs at presynaptic plasma membrane in conjunction with cysteine string protein-alpha/DNAJC5.
Western blot with SNCA Polyclonal antibody at dilution of 1:500.lane 1:SH-SY5Y whole cell lysate, lane 2:Mouse brain, lane 3:Rat brain
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