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SORD Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human; Mouse
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human esophagus cancer
Dilution
IHC 1:50-1:100
Clonality
Polyclonal
Isotype
IgG
Immunogen
Fusion protein of human SORD
Abbre
SORD
Synonyms
DHSO;L iditol 2 dehydrogenase;L-iditol 2-dehydrogenase;OTTHUMP00000161939;SDH;Sorbitol dehydrogenase 1;Sorbitol dehydrogenase;SORD 1;SORD;SORD1抗体
Swissprot
Cellular Localization
Mitochondrion membrane. Cell projection>cilium>flagellum. Associated with mitochondria of the midpiece and near the plasma membrane in the principal piece of the flagellum. Also found in the epididymosome, secreted by the epididymal epithelium and that transfers proteins from the epididymal fluid to the sperm surface.
Concentration
0.78 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method
Antigen affinity purification
Research Areas
Metabolism; Signal Transduction
Conjugation
Unconjugated
Background
Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using SORD Polyclonal Antibody at dilution of 1:45(×200)


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