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STAT6 Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human;Mouse
  • 应用性: WB
Verified Samples
Verified Samples in WB:Raji
Dilution
WB 1:500-1:2000
Clonality
Polyclonal
Isotype
IgG
Immunogen
Recombinant protein of human STAT6
Abbre
STAT6
Synonyms
12S1644;D12S1644;IL 4 STAT;IL-4 Stat;IL4 STAT;Interleukin 4 Induced;Interleukin 4 Induced Transcription Factor IL4 STAT;Signal transducer and activator of transcription 6;Signal Transducer And Activator Of Transcription 6 Interleukin 4 Induced;Signal Transducer And Activator Of Transcription 6 Nirs Variant 1;Signal transducer and activator of transcription 6;interleukin 4 induced;STAT 6;STAT interleukin4 induced;STAT;interleukin4 induced;Stat6;STAT6;STAT6B;STAT6C;Transcription factor IL 4 STAT抗体
Swissprot
Calculated MW
94kDa
Cellular Localization
Cytoplasm. Nucleus. Translocated into the nucleus in response to phosphorylation.
Concentration
0.2 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method
Affinity purification
Research Areas
Cancer; Epigenetics and Nuclear Signaling; Signal Transduction
Conjugation
Unconjugated
Background
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.
Western Blot analysis of Raji cell using STAT6 Polyclonal Antibody at dilution of 1:450
E-AB-1003 Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) 500μL , 120μL , 60μL , 30μL , 1mL
E-AB-1043 Streptavidin(peroxidase/HRP conjugated) 500μL , 120μL , 60μL , 30μL , 1mL
E-AB-1194 HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed 500μL , 120μL , 1mL
E-IR-R304A Western Blot Detection Kit 50Assays
E-IR-R304B High Accuracy and Absorbability Western Blot Detection Kit 50Assays


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