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STK4 Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human;Rat
  • 应用性: WB;IHC
Verified Samples
Verified Samples in WB:293T,Rat liver
Verified Samples in IHC:Rat lung
Dilution
WB 1:500-1:1000;IHC 1:50-1:100
Clonality
Polyclonal
Isotype
IgG
Immunogen
Recombinant human Serine/threonine-protein kinase 4 protein
Abbre
STK4/MST
Synonyms
Antigen NY-CO-13;BCC7;Cellular tumor antigen p53;FLJ92943;LFS1;Mutant tumor protein 53;p53;p53 tumor suppressor;P53;Phosphoprotein p53;Tp53;Transformation related protein 53;TRP53;Tumor protein 53;Tumor protein p53;Tumor suppressor p53抗体
Swissprot
Calculated MW
56 kDa
Observed MW
56 kDa
Cellular Localization
Cytoplasm. Nucleus. The caspase-cleaved form cycles between the nucleus and cytoplasm.
Concentration
2mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Purification Method
Affinity purification
Research Areas
Cancer; Cell Biology; Epigenetics and Nuclear Signaling
Conjugation
Unconjugated
Background
The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.
Western Blot analysis of 293T and Rat liver using STK4 Polyclonal Antibody at dilution of 1:600
Immunohistochemistry of paraffin-embedded Rat lung using STK4 Polyclonal Antibody at dilution of 1:50


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