Survivin Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
- 宿主: Rabbit
- 反应性: Human;Mouse;Rat
- 应用性: WB;IHC
Verified Samples |
Verified Samples in WB:NIH/3T3,Mouse colon,Mouse testis,Mouse skin,Rat colon,Rat testis Verified Samples in IHC:Mouse spleen,Rat spleen |
Dilution | WB 1:500-1:2000;IHC 1:200-1:600 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Recombinant protein corresponding to Mouse Survivin |
Abbre | Survivin |
Synonyms | API4;Apoptosis inhibitor 4;Apoptosis inhibitor survivin;Apoptosis inhibitor4;Baculoviral IAP repeat containing 5;Baculoviral IAP repeat containing protein 5;Baculoviral IAP repeat-containing protein 5;BIRC 5;BIRC5;BIRC5;EPR 1;IAP4;Survivin variant 3 alpha;SVV;TIAP |
Swissprot | |
Calculated MW | 16kDa |
Observed MW | 16-18kDa |
Cellular Localization | Cytoplasm. Nucleus. Chromosome. Chromosome>centromere. Cytoplasm>cytoskeleton>spindle. Localizes on chromosome arms and inner centromeres from prophase through metaphase and then transferring to the spindle midzone and midbody from anaphase through cytokinesis. Colocalizes with AURKB at mitotic chromosomes. |
Concentration | 450 μg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4 |
Purification Method | Affinity purification |
Research Areas | Cancer; Cell Biology; Neuroscience |
Conjugation | Unconjugated |
Background | This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
Western Blot analysis of various samples using Survivin Polyclonal Antibody at dilution of 1:600.
Immunohistochemistry analysis of paraffin-embedded mouse spleen using Survivin Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded rat spleen using Survivin Polyclonal Antibody at dilution of 1:300.
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