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Survivin Polyclonal Antibody

Price: ¥3300 ¥2220 ¥1380

Size:
200μL 120μL 60μL
  • 宿主: Rabbit
  • 反应性: Human;Mouse;Rat
  • 应用性: WB;IHC
Verified Samples
Verified Samples in WB:NIH/3T3,Mouse colon,Mouse testis,Mouse skin,Rat colon,Rat testis
Verified Samples in IHC:Mouse spleen,Rat spleen
Dilution
WB 1:500-1:2000;IHC 1:200-1:600
Clonality
Polyclonal
Isotype
IgG
Immunogen
Recombinant protein corresponding to Mouse Survivin
Abbre
Survivin
Synonyms
API4;Apoptosis inhibitor 4;Apoptosis inhibitor survivin;Apoptosis inhibitor4;Baculoviral IAP repeat containing 5;Baculoviral IAP repeat containing protein 5;Baculoviral IAP repeat-containing protein 5;BIRC 5;BIRC5;BIRC5;EPR 1;IAP4;Survivin variant 3 alpha;SVV;TIAP
Swissprot
Calculated MW
16kDa
Observed MW
16-18kDa
Cellular Localization
Cytoplasm. Nucleus. Chromosome. Chromosome>centromere. Cytoplasm>cytoskeleton>spindle. Localizes on chromosome arms and inner centromeres from prophase through metaphase and then transferring to the spindle midzone and midbody from anaphase through cytokinesis. Colocalizes with AURKB at mitotic chromosomes.
Concentration
450 μg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Purification Method
Affinity purification
Research Areas
Cancer; Cell Biology; Neuroscience
Conjugation
Unconjugated
Background
This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Western Blot analysis of various samples using Survivin Polyclonal Antibody at dilution of 1:600.
Immunohistochemistry analysis of paraffin-embedded mouse spleen using Survivin Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded rat spleen using Survivin Polyclonal Antibody at dilution of 1:300.


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