Vcam1 Polyclonal Antibody

Verified Samples in WB:Mouse spleen,Rat kidney,Rat spleen

WB 1:500-1:1000

Polyclonal

IgG

Recombinant Rat Vcam1 protein expressed by Mammalian

Vcam1

Vcam1;Vcam-1;CD106;V-CAM 1;VCAM-1;Vascular cell adhesion protein 1

81kDa

75-100kDa

1 mg/mL

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

PBS with 0.02% sodium azide, 50% glycerol, pH 7.4

Affinity purification

Unconjugated

Cell adhesion glycoprotein predominantly expressed on the surface of endothelial cells that plays an important role in immune surveillance and inflammation. Acts as a major regulator of leukocyte adhesion to the endothelium through interaction with different types of integrins. During inflammatory responses,binds ligands on the surface of activated endothelial cells to initiate the activation of calcium channels and the plasma membrane-associated small GTPase RAC1 leading to leukocyte transendothelial migration. Serves also as a quality-control checkpoint for entry into bone marrow by providing a 'don't-eat-me' stamping in the context of major histocompatibility complex(MHC) class-I presentation.