Human TG Antibody Pair Set
Price:
Size:
50μL&100μg
- 反应性： Human
| Background |
Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination,and subsequent thyroxine biosynthesis,in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis,manifested as goiter,and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis.
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| Synonyms |
AITD3;TGN
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| Swissprot | |
| Reactivity |
Human
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| Specificity |
Detects Human TG in ELISAs
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| Buffer |
Capture Antibody:PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4; Detection Antibody:PBS with 0.04% Proclin 300, 1% protective protein, 50% glycerol, pH 7.4
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| Storage |
-20℃
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| Expiration date |
12个月
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