流式新选社|23款流式抗体新年上线
Source: Elabscience®Published: 2024-01-10
本次上新23个流式抗体：
Human CD6（克隆号HI210）和Human CD7（克隆号HIT7）2个新指标共7种流式抗体，
Human CD2、Human CD5、Human CD11a等已有指标16种流式抗体。
Human CD6抗体
（克隆号HI210）
HI210是一种对CD6抗原具有特异性的抗人单克隆抗体。CD6一般表达于大多数的成熟T细胞、一小部分B细胞以及约50%的NK细胞的表面。CD6是CD166/ALCAM（活化白细胞粘附分子）和CD318（CDCP1，含CUB结构域的蛋白1）的受体。这两种分子会在大多数癌细胞中呈高表达。CD166和CD318都参与T淋巴细胞的CD6依赖性粘附。CD6 正成为许多自身免疫性疾病的诱人治疗靶点，因为遗传性 CD6 缺失或使用抗 CD6 单克隆抗体（mAb）治疗可防止甚至逆转自身免疫性疾病。本次上线3个克隆号为HI210的Human CD6抗体。
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货号 |
名称 |
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E-AB-F1314C |
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E-AB-F1314D |
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E-AB-F1314E |
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Human peripheral blood lymphocytes are stained with APC Anti-Human CD6 Antibody[HI210] (filled gray histogram) or APC Mouse IgG1, κ Isotype Control (empty black histogram).
Human CD7抗体
（克隆号HIT7）
HIT7是一种识别CD7抗原的抗人单克隆抗体。CD7（也称为gp40）是一种40kD的单程I型膜蛋白，表达于NK细胞、干细胞和T细胞等细胞的表面。CD7与免疫反应，特别是与适应性免疫反应等重要生物过程密切相关。此外，它还参与重要的细胞通路，即跨膜受体蛋白酪氨酸激酶信号通路。在临床应用中，CD7的检测常用于血液病特别是白血病和淋巴瘤类型的诊断和亚型分类，同时，CD7也可以作为免疫治疗中的潜在靶点。本次上线3个克隆号为HIT7的Human CD7抗体。
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货号 |
名称 |
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E-AB-F1315C |
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E-AB-F1315D |
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E-AB-F1315E |
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Human peripheral blood lymphocytes are stained with APC Anti-Human CD3 Antibody and PE Anti-Human CD7 Antibody[HIT7] (Left). Lymphocytes are stained with APC Anti-Human CD3 Antibody and PE Mouse IgG1, κ Isotype Control (Right).
Human CD2、Human CD5、Human CD11a抗体
除了Human CD6和Human CD7这两个新指标外，本次还上线了另外16个流式抗体，为已有指标新增克隆号，涉及Human CD2、Human CD5、Human CD11a。
Human peripheral blood lymphocytes are stained with APC Anti-Human CD19 Antibody and PE Anti-Human CD2 Antibody[HIT11] (Left). Lymphocytes are stained with APC Anti-Human CD19 Antibody and PE Mouse IgG1, κ Isotype Control (Right).
Human peripheral blood lymphocytes are stained with APC Anti-Human CD19 Antibody and FITC Anti-Human CD5 Antibody[HISM2] (Left). Lymphocytes are stained with APC Anti-Human CD19 Antibody and FITC Mouse IgG1, κ Isotype Control (Right).
Human peripheral blood lymphocytes are stained with FITC Anti-Human CD11a Antibody[HI111] (filled gray histogram) or FITC Mouse IgG1, κ Isotype Control (empty black histogram).
