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APC Anti-Rat CD161 Antibody[3.2.3]

Uniprot : P27471,A4KWA1,Q5NKN4,Q5NKN2

货号: E-AB-F1307E
应用: FCM
Isotype: Mouse IgG1, κ
宿主: Mouse

Applications:

说明书

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规格:

50Tests
100Tests
100Tests×2

价格: ￥960

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Antigen Details

Alternate Names	NKR-P1, CD161a/CD161b, NKR-P1a/KLRB1a
Swissprot	P27471,A4KWA1,Q5NKN4,Q5NKN2
Gene ID	362443
References	1. Chambers WH, et al. 1989. J. Exp. Med. 169:1373. 2. Brink M, et al. 1990. J. Exp. Med. 171:197. 3. Li J, et al. 2003. Int. Immunol. 15:411.

Product Details

Form	Liquid
Clone No.	3.2.3 (See Other Available Formats)
Host	Mouse
Isotype	Mouse IgG1, κ
Isotype Control	APC Mouse IgG1, κ Isotype Control[MOPC-21] [Product E-AB-F09792E]
Reactivity	Rat
Application	FCM (See the Application Description)
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Recommended Use	Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Shipping	Biological ice pack at 4℃
Stability & Storage	Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Conjugation	APC
	APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter).

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Background

CD161 is a 30 kD type II transmembrane C-type lectin, expressed as a homodimer. Rat NKR-P1 receptors are primarily expressed on NK cells, a subset of T cells, dendritic cells, and activated monocytes. There are three different types of NKR-P in rat, namely NKR-P1a, NKR-P1b, and NKR-P1c. NKR-P1a does not contain an ITIM structure and is an activating receptor, while NKR-P1b contains an ITIM and displays inhibitory function. LLT-1 (ligand lectin like transcript 1) is the ligand, while KLR (killer cell lectin like) functions as a receptor.

Protocols & Troubleshootings

Related Protocols	流式细胞表面染色步骤
Troubleshooting	流式实验常见问题及解决方案

Alternative Formats

Cat.No.	Product Name	Sizes
E-AB-F1307C	FITC Anti-Rat CD161 Antibody[3.2.3]	50Tests, 100Tests, 100Tests×2
E-AB-F1307D	PE Anti-Rat CD161 Antibody[3.2.3]	50Tests, 100Tests, 100Tests×2