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CTSB Polyclonal Antibody

CTSB Polyclonal Antibody
  • CTSB Polyclonal Antibody
  • CTSB Polyclonal Antibody

Price: ¥2100.00 ¥800.00

Size:
100 μL 25 μL
  • 宿主: Rabbit
  • 反应性: Human
  • 应用性: WB
Verified Samples
Verified Samples in WB: Human HepG2
Dilution
WB 1:500-1:1000
Clonality
Polyclonal
Isotype
IgG
Immunogen
Recombinant Human CTSB protein expressed by Mammalian
Abbre
CTSB
Synonyms
APP secretase, APPS, Amyloid precursor protein secretase, CATB, CPSB, CTSB, Cathepsin B heavy chain, Cathepsin B1, CathepsinB, OTTHU, OTTHUMP00000116009, OTTHUMP00000229510, OTTHUMP00000229511, OTTHUMP00000229512, OTTHUMP00000229514, OTTHUMP00000229515, cysteine protease
Swissprot
Calculated MW
38 kDa
Observed MW
44/27/24 kDa
Cellular Localization
Lysosome Melanosome Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Concentration
1 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4
Purification Method
Antigen Affinity Purification
Research Areas
Cancer, Neuroscience, Signal Transduction
Conjugation
Unconjugated
Background
The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains,both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease,the most common cause of dementia. Overexpression of the encoded protein,which is a member of the peptidase C1 family,has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene.
Western blot with CTSB Polyclonal antibody at dilution of 1:1000.lane 1:HepG2 whole cell lysate
E-AB-1003 Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) 500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1043 Streptavidin(peroxidase/HRP conjugated) 500 μL , 120 μL , 60 μL , 30 μL , 1 mL
E-AB-1194 HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed 500 μL , 120 μL , 1 mL
E-IR-R304A Western Blot Detection Kit 50 Assays
E-IR-R304B High Accuracy and Absorbability Western Blot Detection Kit 50 Assays


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