CTSB Polyclonal Antibody

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- 宿主: Rabbit
- 反应性: Human
- 应用性: WB
Verified Samples |
Verified Samples in WB: Human HepG2 |
Dilution | WB 1:500-1:1000 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Recombinant Human CTSB protein expressed by Mammalian |
Abbre | CTSB |
Synonyms | APP secretase, APPS, Amyloid precursor protein secretase, CATB, CPSB, CTSB, Cathepsin B heavy chain, Cathepsin B1, CathepsinB, OTTHU, OTTHUMP00000116009, OTTHUMP00000229510, OTTHUMP00000229511, OTTHUMP00000229512, OTTHUMP00000229514, OTTHUMP00000229515, cysteine protease |
Swissprot | |
Calculated MW | 38 kDa |
Observed MW | 44/27/24 kDa |
Cellular Localization | Lysosome Melanosome Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
Concentration | 1 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4 |
Purification Method | Antigen Affinity Purification |
Research Areas | Cancer, Neuroscience, Signal Transduction |
Conjugation | Unconjugated |
Background | The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains,both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease,the most common cause of dementia. Overexpression of the encoded protein,which is a member of the peptidase C1 family,has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene. |
E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500 μL , 120 μL , 60 μL , 30 μL , 1 mL |
E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500 μL , 120 μL , 60 μL , 30 μL , 1 mL |
E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500 μL , 120 μL , 1 mL |
E-IR-R304A | Western Blot Detection Kit | 50 Assays |
E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50 Assays |