FITC Anti-Human CD45 Antibody[HI30]
![FITC Anti-Human CD45 Antibody[HI30]](http://files.elabscience.cn/assets/images/loading.png)
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- 应用性: FCM
- 亚型: Mouse IgG1, κ
- 宿主: Mouse
Alternate Names | CD45, L-CA, Ly-5, Ptprc, Receptor-type tyrosine-protein phosphatase C, T200 |
Cellular Localization |
Membrane
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Clone No | |
Isotype | Mouse IgG1, κ |
Leadtime |
咨询
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Background |
CD45 is a 180 - 240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes or platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4.
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Abbre | CD45 |
Swissprot | |
Host | Mouse |
Reactivity | Human |
Clonality | Monoclonal |
Isotype Control | |
Applications | |
Form | Liquid |
Concentration | 5 μL/Test |
Conjugation | FITC |
Conjugation Information | FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter). |
Spectrum | ![]() |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
Expiration Date | 12个月 |
Shipping |
冰袋 |
Gene ID |
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EMF treatment delays mesenchymal stem cells senescence during long-term in vitro expansion by modulating autophagy
IF: 4.600Journal: Frontiers in Cell and Developmental Biology (2024)Reactivity:Rat -
CA1 Modulates the Osteogenic Differentiation of Dental Follicle Stem Cells by Activating the BMP Signaling Pathway In Vitro
IF: 4.400Journal: Tissue Engineering and Regenerative Medicine (2024)Reactivity:Human -
PSO/SDF-1 composite hydrogel promotes osteogenic differentiation of PDLSCs and bone regeneration in periodontitis rats
IF: 3.400 -
Impact of Strontium, Magnesium, and Zinc Ions on the In Vitro Osteogenesis of Maxillary Sinus Membrane Stem Cells
IF: 3.400 -
Plexin-B2 Mediates Orthodontic Tension-Induced Osteogenesis via the RhoA/F-Actin/YAP Pathway
IF: 3.400 -
A transcriptomic analysis of dental pulp stem cell senescence in vitro
IF: 2.900 -
Effect of psoralen on the regulation of osteogenic differentiation induced by periodontal stem cell-derived exosomes
IF: 4.300 -
Biomimetic Black Phosphorus Nanosheet-Based Drug Delivery System for Targeted Photothermal-Chemo Cancer Therapy
IF: 5.890 -
Differentiation potential and mRNA profiles of human dedifferentiated adipose cells and adipose?derived stem cells from young donors
IF: 2.952Journal: Molecular Medicine Reports (2021)PMID:33200799Reactivity:HumanSample Type:Dedifferentiated adipose cells , Adipose?derived stem cells -
Notum suppresses the osteogenic differentiation of periodontal ligament stem cells through the Wnt/Beta catenin signaling pathway
IF: 2.635
E-CK-A105 | 10×ACK Lysis Buffer | 500mL , 200mL , 100mL |
E-CK-A107 | Cell Staining Buffer | 500mL , 200mL , 100mL |