PE/Cyanine7 Anti-Human CD196/CCR6 Antibody[G034E3]
Price:
Size:
100Tests
20Tests
100Tests×2
- 应用性: FCM
- 亚型: Mouse IgG2b, κ
- 宿主: Mouse
Background | CCR6, also known as CD196/CCR6, is a chemokine receptor that is expressed on immature dendritic cells, B lymphocytes, and memory T cells. CCR6 binds CCL20, although members of the β defensin family also bind CCR6 with a lower affinity. CCR6 positive cells, and its ligand CCL20, have been detected in numerous organs, especially the secondary lymphoid organ. CCL20 is selectively made by the follicle-associated epithelium (FAE) overlying Peyers Patches (PPs) and isolated lymphoid follicles (ILFs). CCL20 contributes to the recruitment of CCR6-expressing B cells to these structures. In humans, CCR6 can function to mediate arrest of T cells on dermal endothelial cells and is highly expressed on T cells resident in both normal and psoriatic skin. CCR6 and/or CCL20 have been implicated in the pathogenesis of rheumatoid arthritis and inflammatory bowel disease. Human T cells that are able to produce IL-17 express CCR6. It suggests that CCL20 and CCR6 have a role in inflammatory diseases by recruiting Th17 cells to target tissues. |
Alternate Names | CKRL3; CMKBR6; GPR29; STRL22;GPRCY4; |
Swissprot | |
Gene ID | |
Clone No | |
Host | Mouse |
Reactivity | Human |
Application | |
Isotype | Mouse IgG2b, κ |
Isotype Control | |
Conjugation | PE/Cyanine 7 |
Conjugation Information | PE/Cyanine7 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 775 nm (e.g., a 780/60 nm bandpass filter). |
Spectrum | |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
Expiration date | 12个月 |
Shipping |
冰袋 |
Human peripheral blood lymphocytes are stained with PE/Cyanine7 Anti-Human CD196/CCR6 Antibody and FITC Anti-Human CD19 Antibody.
E-AB-F1158C | FITC Anti-Human CD196/CCR6 Antibody[G034E3] | 100Tests , 20Tests , 100Tests×2 |
E-AB-F1158D | PE Anti-Human CD196/CCR6 Antibody[G034E3] | 100Tests , 20Tests , 100Tests×2 |
E-AB-F1158E | APC Anti-Human CD196/CCR6 Antibody[G034E3] | 100Tests , 20Tests , 100Tests×2 |
E-AB-F1158M | Elab Fluor® 647 Anti-Human CD196/CCR6 Antibody[G034E3] | 100Tests , 20Tests , 100Tests×2 |
E-AB-F1158Q | Elab Fluor® Violet 450 Anti-Human CD196/CCR6 Antibody[G034E3] | 100Tests , 20Tests , 100Tests×2 |