PerCP/Cyanine5.5 Anti-Human CD279/PD-1 Antibody[EH12.2H7]
Price:
Size:
100Tests
20Tests
100Tests×2
- 应用性: FCM
- 亚型: Mouse IgG1, κ
- 宿主: Mouse
Background | Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 and PD-L2 are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion. |
Alternate Names | PDCD1;PD1;Protein PD-1;hPD-1; |
Swissprot | |
Gene ID | |
Clone No | |
Host | Mouse |
Reactivity | Human |
Application | |
Isotype | Mouse IgG1, κ |
Isotype Control | |
Conjugation | PerCP/Cyanine 5.5 |
Conjugation Information | PerCP/Cyanine5.5 is designed to be excited by the blue laser (488 nm) and detected using an optical filter centered near 675 nm (e.g., a 690/50 nm bandpass filter). |
Spectrum | |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
Expiration date | 12个月 |
Shipping |
冰袋 |
MOLT-4 cells treated with 500 ng/ml Ionomycin and 10 ng/ml Phorbol-12-myristate-13-acetate (PMA) for 24 hours are stained with PerCP/Cyanine5.5 Anti-Human CD279/PD-1 Antibody (filled gray histogram) or PerCP/Cyanine5.5 Mouse IgG1, κ Isotype Control (empty black histogram).
E-AB-F1229C | FITC Anti-Human CD279/PD-1 Antibody[EH12.2H7] | 100Tests , 20Tests , 100Tests×2 |
E-AB-F1229D | PE Anti-Human CD279/PD-1 Antibody[EH12.2H7] | 100Tests , 20Tests , 100Tests×2 |
E-AB-F1229E | APC Anti-Human CD279/PD-1 Antibody[EH12.2H7] | 100Tests , 20Tests , 100Tests×2 |