Recombinant Cynomolgus PD-L2/B7-DC/CD273 Protein (Fc Tag)
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- 表达系统： HEK293 Cells
- 蛋白编码： A4GW30
| 别称 |
Programmed Cell Death 1 Ligand 2;PD-1 Ligand 2;PD-L2;PDCD1 Ligand 2;Programmed Death Ligand 2;Butyrophilin B7-DC;B7-DC;CD273;PDCD1LG2;B7DC;CD273;PDCD1L2;PDL2
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| 表达系统 |
HEK293 Cells
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| 序列 |
Leu20-Pro219
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| 蛋白编码 |
A4GW30
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| 种属 |
Cynomolgus macaques
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| 计算分子量 |
49.5 kDa
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| 表观分子量 |
60-90 kDa
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| 标签 |
C-Fc
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| 纯度 |
> 95 % as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
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| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
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| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
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| 制剂 |
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| 复溶方法 |
Please refer to the printed manual for detailed information.
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| 背景 |
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) is a member of the BTN/MOG family. PDCD1LG2 contains one Ig-like C2-type domain and one Ig-like V-type domain. PDCD1LG2 is highly expressed in the heart, placenta, pancreas, lung and liver; it is weakly expressed in the spleen, lymph nodes, and thymus. PDCD1LG2 is involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PDCD1LG2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
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实验操作视频
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