• 本公司产品仅供体外研究使用,不用于临床诊断

Recombinant Human ACE2 Protein (mFc Tag)

  • Recombinant Human ACE2 Protein (mFc Tag)-Elabscience
<
>
  • Recombinant Human ACE2 Protein (mFc Tag)-Elabscience
  • Recombinant Human ACE2 Protein (mFc Tag)-Elabscience
    产品货号:PKSR030494

    别称:Angiotensin-Converting Enzyme 2, ACE-Related Carboxypeptidase, Angiotensin-Converting Enzyme Homolog, ACEH, Metalloprotease MPROT15, ACE2

    规格:
    • 10μg
    • 50μg
    数量:
    - +
    价格: ¥1248

    Expression_host: Human Cell

    Accession: Q9BYF1

    Overview

    Synonyms Angiotensin-Converting Enzyme 2, ACE-Related Carboxypeptidase, Angiotensin-Converting Enzyme Homolog, ACEH, Metalloprotease MPROT15, ACE2
    Expression host Human Cell
    Sequence Gln18-Ser740
    Accesstion Q9BYF1
    Species Human
    Mol_Mass 110 kDa
    AP_Mol_Mass 110-140 kDa
    Tag C-mFc
    Bio_Activity Immobilized 2019-nCoV S1 Protein-Fc(Cat#PKSR030480) at 10μg/ml (100 μl/well) can bind Human ACE-2-mFc(Cat#PKSR030494). The ED50 of PKSR030494 is 0.58 ug/ml.

    Properties

    Purity > 95 % as determined by reducing SDS-PAGE.
    Endotoxin < 1.0 EU per g as determined by the LAL method.
    Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
    Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt; store it immediately at<-20°C.
    Formulation Supplied as a 0.2 μM filtered solution of 20mM Tris-HCl, 300mM NaCl, 1mM ZnCl2, 10% Glycerol, pH 7.4.
    Reconstitution Please refer to the printed manual for detailed information.

    Background

    Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don’t inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.

    Images

    写评论得优惠
    • 全部 (0)
    • 评论 (0)
    • 问答 (0)
    ... 展开 收起

    我的购物车

    产品名称 数量 价格
    结算

    总计:

    诚邀您参与Elabscience生化试剂盒性能验证计划还有积分奖励等你来赢!

    浏览历史


      买了该产品的人还买了