Recombinant Human Apolipoprotein C-II/APOC2 Protein (His Tag)
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- 表达系统： E.coli
- 蛋白编码： AAP35354.1
| 别称 |
Apolipoprotein C-II;Apolipoprotein C2;APC2 and APOC2
|
| 表达系统 |
E.coli
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| 序列 |
Thr23-Glu101
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| 蛋白编码 |
AAP35354.1
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| 种属 |
Human
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| 计算分子量 |
10.0 kDa
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| 表观分子量 |
14 kDa
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| 标签 |
C-His
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| 纯度 |
> 95 % as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
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| 保存条件 |
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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| 运输条件 |
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
|
| 制剂 |
Supplied as a 0.2 μm filtered solution of PBS, 50% Glycerol, pH 7.4.
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| 复溶方法 |
Not Applicable
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| 背景 |
APOC2 activates the lipoprotein lipase in capillaries, which hydrolyzes triglycerides and thus provides free fatty acids for cells. APOC2 is component of the very low density lipoprotein (VLDL) fraction in plasma. It is also an activator of several triacylglycerol lipases. The association of APOC2 with plasma chylomicrons, VLDL, and HDL is reversible, a function of the secretion and catabolism of triglyceride-rich lipoproteins, and changes rapidly. Defects in APOC2 are the cause of hyperlipoproteinemia type 1B (HLPP1B) which characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis.
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实验操作视频
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