Recombinant Human ASXL1 Protein (GST Tag)
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- 表达系统： E.coli
- 蛋白编码： Q8IXJ9
| 别称 |
Putative Polycomb group protein ASXL1;Additional sex combs-like protein 1;ASXL1;KIAA0978;
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| 表达系统 |
E.coli
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| 序列 |
Lys1477-Arg1541
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| 蛋白编码 |
Q8IXJ9
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| 种属 |
Human
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| 计算分子量 |
33.6 kDa
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| 表观分子量 |
38 kDa
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| 标签 |
N-GST
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| 纯度 |
> 90 % as determined by reducing SDS-PAGE.
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| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
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| 保存条件 |
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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| 运输条件 |
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
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| 制剂 |
Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
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| 复溶方法 |
Not Applicable
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| 背景 |
Putative Polycomb group protein ASXL1 involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as retinoic acid receptors (RARs) and peroxisome proliferator-activated receptor gamma (PPARG). It acts as coactivator of RARA and RXRA through association with NCOA1. ASXL1 also acts as corepressor through recruitment of KDM1A and CBX5 to target genes in a cell-type specific manner; the function seems to involve differential recruitment of methylated histone H3 to respective promoters.
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实验操作视频
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