Recombinant Human BAG2 Protein (His Tag)
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- 表达系统： E.coli
- 蛋白编码： O95816
| 别称 |
BAG Family Molecular Chaperone Regulator 2;BAG-2;Bcl-2-Associated Athanogene 2;BAG2
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| 表达系统 |
E.coli
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| 序列 |
Met 1-Asn211
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| 蛋白编码 |
O95816
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| 种属 |
Human
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| 计算分子量 |
25.9 kDa
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| 表观分子量 |
25-30 kDa
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| 标签 |
N-His
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| 纯度 |
> 90 % as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
|
| 保存条件 |
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
|
| 运输条件 |
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
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| 制剂 |
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM EDTA, 1mM DTT, 10% Glycerol, pH8.0.
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| 复溶方法 |
Not Applicable
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| 背景 |
BAG Family Molecular Chaperone Regulator 2 (BAG2) is a member of the Bag family whose members compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. BAG2 contains 1 BAG domain and is a important component of the HSC 70/CHIP chaperone-dependent ubiquitin ligase complex. In mammalian cells BAG1, BAG2, and BAG3 bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
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实验操作视频
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