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Recombinant Human Cathepsin B/CTSB Protein (His Tag)

  • Recombinant Human Cathepsin B/CTSB Protein(C-6His)-Elabscience
  • Recombinant Human Cathepsin B/CTSB Protein (His Tag)-Elabscience
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  • Recombinant Human Cathepsin B/CTSB Protein(C-6His)-Elabscience
  • Recombinant Human Cathepsin B/CTSB Protein (His Tag)-Elabscience
  • Recombinant Human Cathepsin B/CTSB Protein(C-6His)-Elabscience
  • Recombinant Human Cathepsin B/CTSB Protein (His Tag)-Elabscience
    产品货号:PKSH032179

    别称:Cathepsin B, APP Secretase, APPS, Cathepsin B1, CTSB, CPSB

    规格:
    • 10μg
    • 50μg
    数量:
    - +
    价格: ¥2624

    Expression_host: Human Cell

    Accession: P07858

    Overview

    Synonyms Cathepsin B, APP Secretase, APPS, Cathepsin B1, CTSB, CPSB
    Expression host Human Cell
    Sequence Arg18-Ile339
    Accesstion P07858
    Species Human
    Mol_Mass 36.9 kDa
    AP_Mol_Mass 40 kDa
    Tag C-6His

    Properties

    Purity > 95 % as determined by reducing SDS-PAGE.
    Endotoxin < 1.0 EU per g as determined by the LAL method.
    Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
    Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt; store it immediately at<-20°C.
    Formulation Supplied as a 0.2 μM filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
    Reconstitution Please refer to the printed manual for detailed information.

    Background

    Cathepsin B is an enzymatic protein belonging to the peptidase (or protease) families. The protein encoded by this gene is a lysosomal cysteine protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is a member of the peptidase C1 family. At least five transcript variants encoding the same protein have been found for this gene. Cystatin-B / CSTB is an intracellular thiol proteinase inhibitor. Tightly binding reversible inhibitor of cathepsins L, H and B. Cystatin-B / CSTB is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. Cystatin-B / CSTB is also thought to play a role in protecting against the proteases leaking from lysosomes

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