Recombinant Human CD200R1 Protein (Fc Tag)
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- 表达系统： HEK293 Cells
- 蛋白编码： Q8TD46
| 别称 |
Cell Surface Glycoprotein CD200 Receptor 1;CD200 Cell Surface Glycoprotein Receptor;Cell Surface Glycoprotein OX2 Receptor 1;CD200R1;CD200R;CRTR2;MOX2R;OX2R
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| 表达系统 |
HEK293 Cells
|
| 序列 |
Ala27-Leu266
|
| 蛋白编码 |
Q8TD46
|
| 种属 |
Human
|
| 计算分子量 |
53.9 kDa
|
| 表观分子量 |
70-105 kDa
|
| 标签 |
C-Fc
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| 纯度 |
> 95 % as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
|
| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
|
| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
|
| 制剂 |
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| 复溶方法 |
Please refer to the printed manual for detailed information.
|
| 背景 |
Cell surface glycoprotein CD200 Receptor 1 (CD200R1) is the receptor for the CD200 (OX-2) membrane glycoprotein. CD200R1 contains one C2- type Ig-like domain and one V-type Ig-like domain within its extracellular domain and a PTB-signaling motif in cytoplasmic domain. CD200R1 and CD200 associate via their respective N-terminal Ig-like domains. CD200R1 is restricted primarily to mast cells, basophils, macrophages, and dendritic cells. It propagates inhibitory signals despite its lacking a cytoplasmic ITIM (immunoreceptor tyrosinebased inhibitory motif). The receptor-substrate interaction may function as a myeloid downregulatory signal.
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实验操作视频
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