Recombinant Human CD62L/L-Selectin protein (His tag)
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- 表达系统： E.coli
- 蛋白编码： P30836
| 别称 |
L-selectin;Sell;CD62 antigen-like family member L;Leukocyte adhesion molecule 1 (LAM-1);Leukocyte-endothelial cell adhesion molecule 1;Lymph node homing receptor;Lymphocyte antigen 22 (Ly-22);Lymphocyte surface MEL-14 antigen;CD62L
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| 表达系统 |
E.coli
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| 序列 |
Trp 39-Asn 332
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| 蛋白编码 |
P30836
|
| 种属 |
Human
|
| 计算分子量 |
32.2 kDa
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| 表观分子量 |
39 kDa
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| 标签 |
N-His
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| 纯度 |
> 95 % as determined by reducing SDS-PAGE.
|
| 内毒素 |
Please contact us for more information.
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| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
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| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
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| 制剂 |
Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| 复溶方法 |
Please refer to the printed manual for detailed information.
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| 背景 |
L-Selectin (also known as Leukocyte Selectin, LAM?1, LECAM-1, LECCAM-1, TQ1, Leu-8, MEL-14 antigen, DREG, lymph node homing receptor, CD62L), a member of the Selectin family, is a cell surface glycoprotein expressed constitutively on a wide variety of leukocytes. Two forms of L?Selectin have been reported, apparently arising as a result of post-translational modifications. The lymphocyte form shows an apparent molecular weight of 74 kDa, while the neutrophil form is 90 - 100 kDa. Human and mouse L?Selectin share 76% amino acid (aa) sequence homology.L?Selectin plays a role in the migration of lymphocytes into peripheral lymph nodes and sites of chronic inflammation, and of neutrophils into acute inflammatory sites. Acting in cooperation with P-Selectin and E-Selectin, L?Selectin mediates the initial interaction of circulating leukocytes with endothelial cells that produces a characteristic "rolling" of the leukocytes on the endothelium. This initial interaction, also involving ICAM-1 and VCAM-1, leads eventually to extravasation of the white blood cell through the blood vessel wall into the extracellular matrix tissue.
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实验操作视频
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