Recombinant Human CD96 Protein (His Tag)
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- 表达系统： HEK293 Cells
- 蛋白编码： P40200-2
- 应用性： BLI
| 别称 |
T-cell surface protein tactile;Cell surface antigen CD96;T cell-activated increased late expression protein;CD96
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| 表达系统 |
HEK293 Cells
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| 序列 |
Val22-Met503
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| 蛋白编码 |
P40200-2
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| 种属 |
Human
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| 计算分子量 |
54.4 kDa
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| 表观分子量 |
120-150 kDa
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| 标签 |
C-His
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| 生物活性 |
Loaded Human PVR-Fc on Protein A Biosensor, can bind Human CD96-His with an affinity constant of 0.12 uM as determined in BLI assay.
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| 纯度 |
> 90 % as determined by reducing SDS-PAGE.
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| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
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| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
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| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
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| 制剂 |
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| 复溶方法 |
Please refer to the printed manual for detailed information.
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| 背景 |
The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. The CD155 ligand CD96 is a member of the Ig superfamily. It's a immunoglobulin-like protein tentatively allocated to the repertoire of human NK receptors. NK cells recognize poliovirus receptor (PVR); anectins and nectin-like protein family member serve to mediate cell-cell adhesion; cell migration; with the presence of an additional receptor; CD96. CD96 promotes NK cell adhesion to target cells expressing PVR; stimulates cytotoxicity of activated NK cells; and mediates acquisition of PVR from target cells.
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实验操作视频
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