Recombinant Human Cystathionine γ-Lyase/CTH Protein
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- 表达系统: E.coli
- 蛋白编码: P32929
别称 |
Cystathionine Gamma-Lyase;Cysteine-Protein Sulfhydrase;Gamma-Cystathionase;CTH
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表达系统 |
E.coli
|
序列 |
Met 1-Ser405
|
蛋白编码 |
P32929
|
种属 |
Human
|
计算分子量 |
44.7 kDa
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表观分子量 |
38-50 kDa
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标签 |
None
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纯度 |
> 85 % as determined by reducing SDS-PAGE.
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内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
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保存条件 |
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
|
运输条件 |
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
|
制剂 |
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 8% Sucrose, 0.05% Tween 80, pH8.0.
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复溶方法 |
Not Applicable
|
背景 |
Cystathionine Gamma-Lyase (CTH) belongs to the trans-sulfuration enzymes family. CTH exists as a homotetramer and interacts with CALM in a calcium-dependent manner. CTH breaks down cystathionine into cysteine, ammonia and 2-oxobutanoate. CTH catalyzes the last step in the trans-sulfuration pathway from methionine to cysteine and has broad substrate specificity. Defects in CTH will lead to cystathioninuria, which is an autosomal recessive phenotype characterized by abnormal accumulation of plasma cystathionine.
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实验操作视频
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