Recombinant Human DFFA Protein (His Tag)
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- 表达系统： E.coli
- 蛋白编码： AAH07721.1
| 别称 |
DNA Fragmentation Factor Subunit Alpha;DNA Fragmentation Factor 45 kDa Subunit;DFF-45;Inhibitor of CAD;ICAD;DFFA;DFF1;DFF45;H13
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| 表达系统 |
E.coli
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| 序列 |
Met 1-Thr331
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| 蛋白编码 |
AAH07721.1
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| 种属 |
Human
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| 计算分子量 |
38.7 kDa
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| 表观分子量 |
40-50 kDa
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| 标签 |
N-His
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| 纯度 |
> 85 % as determined by reducing SDS-PAGE.
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| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
|
| 保存条件 |
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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| 运输条件 |
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
|
| 制剂 |
Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
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| 复溶方法 |
Not Applicable
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| 背景 |
DNA Fragmentation Factor Subunit Alpha (DFFA). DFFA exists as a heterodimer (DFF) with DFFB. DFF is activated once DFFA is cleaved by Caspase-3. The cleaved fragments of DFFA detach from DFFB (the active component of DFF), which in turn triggers DNA fragmentation as well as chromatin condensation during apoptosis. A reduced level of DFFA detected in ovarian endometriosis may be a part of an apoptosis-resistant mechanism enhancing the disease progression.
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实验操作视频
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