Recombinant Human GAS6 (C-6His)
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- 表达系统： HEK293 Cells
- 蛋白编码： Q14393-2
- 应用性： ELISA
| 别称 |
AXLLG;AXLLGAXL stimulatory factor;AXSFAXL receptor tyrosine kinase ligand;Gas6;GAS-6;growth arrest-specific 6;growth arrest-specific protein 6
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| 表达系统 |
HEK293 Cells
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| 序列 |
Ala31-Ala678
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| 蛋白编码 |
Q14393-2
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| 种属 |
Human
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| 计算分子量 |
72.7 kDa
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| 表观分子量 |
80-90 kDa
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| 标签 |
C-His
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| 生物活性 |
Immobilized Human AXL-His at 10μg/ml (100 μl/well) can bind Human GAS6-His : Biotinylated by NHS-biotin prior to testing. The ED50 of Recombinant Human GAS6-His is 0.04466 ug/ml.
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| 纯度 |
> 95 % as determined by reducing SDS-PAGE.
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| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
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| 保存条件 |
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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| 运输条件 |
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
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| 制剂 |
Supplied as a 0.2 μm filtered solution of PBS, 10% Glycerol, pH 7.4.
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| 复溶方法 |
Not Applicable
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| 背景 |
GAS6 (Growth arrest-specific protein 6) is also known as AXL receptor tyrosine kinase ligand, AXLLG, is a multimodular protein that is up-regulated by a wide variety of cell types in response to growth arrest. Gas6 binds and induces signaling through the receptor tyrosine kinases Axl, Dtk, and Mer whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.
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实验操作视频
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