Recombinant Human GSTP1 Protein
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- 表达系统： E.coli
- 蛋白编码： AAH10915.1
| 别称 |
Glutathione S-transferase P;GSTP1;GST class-pi;GSTP1-1;FAEES3;GST3;
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| 表达系统 |
E.coli
|
| 序列 |
Met 1-Glu210
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| 蛋白编码 |
AAH10915.1
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| 种属 |
Human
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| 计算分子量 |
23.5 kDa
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| 表观分子量 |
22-25 kDa
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| 标签 |
None
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| 纯度 |
> 95 % as determined by reducing SDS-PAGE.
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| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
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| 保存条件 |
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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| 运输条件 |
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
|
| 制剂 |
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH 8.0.
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| 复溶方法 |
Not Applicable
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| 背景 |
Glutathione S-transferase P (GSTP1) is an enzyme that contains 1 GST C-terminal domain, 1 GST N-terminal domain. GSTP1 belongs to the GST superfamily, the GSTs are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. The glutathione S-transferase pi gene (GSTP1) is a polymorphic gene encoding active, functionally different GSTP1 variant proteins. Besides, it regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration. It thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.
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实验操作视频
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