Recombinant Human HSPB8 Protein (His Tag)
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- 表达系统： E.coli
- 蛋白编码： Q9UJY1
| 别称 |
Heat shock protein beta-8;HspB8;Alpha-crystallin C chain;E2-induced gene 1 protein;Protein kinase H11;Small stress protein-like protein HSP22;HSPB8;CRYAC;E2IG1;HSP22
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| 表达系统 |
E.coli
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| 序列 |
Met 1-Thr196
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| 蛋白编码 |
Q9UJY1
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| 种属 |
Human
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| 计算分子量 |
22.7 kDa
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| 表观分子量 |
23 kDa
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| 标签 |
C-His
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| 纯度 |
> 95 % as determined by reducing SDS-PAGE.
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| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
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| 保存条件 |
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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| 运输条件 |
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
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| 制剂 |
Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 5mM EDTA, pH 7.4.
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| 复溶方法 |
Not Applicable
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| 背景 |
Heat shock protein beta-8 (HSPB8) belongs to the small heat shock protein (HSP20) family. This protein can be inducted by 17-beta-estradiol, and is predominantly expressed in skeletal muscle and heat, mainly located in the cytoplasm and nucleus. HSPB8 usually exists in monomer, it can interact with HSPB1 and DNAJB6. HSPB8 displays temperature-dependent chaperone activity,appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.
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实验操作视频
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