Recombinant Human IL-1A/IL-1α Protein
Price:
- 表达系统： E.coli
- 蛋白编码： P01583
- 应用性： Cell culture
| 别称 |
Interleukin-1 Alpha;IL-1 Alpha;Hematopoietin-1;IL1A;IL1F1
|
| 表达系统 |
E.coli
|
| 序列 |
Ser113-Ala271
|
| 蛋白编码 |
P01583
|
| 种属 |
Human
|
| 计算分子量 |
19 kDa
|
| 表观分子量 |
17 kDa
|
| 标签 |
C-His
|
| 生物活性 |
Measure by its ability to induce D10.G4.1 cells proliferation.The ED50 for this effect is <10 pg/mL. The specific activity of recombinant human IL-1 alpha is approximately >1x108IU/ mg.
|
| 纯度 |
> 98 % as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 0.1 EU per μg of the protein as determined by the LAL method.
|
| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
|
| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
|
| 制剂 |
Lyophilized from sterile PBS,pH 8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| 复溶方法 |
Please refer to the printed manual for detailed information.
|
| 背景 |
Interleukin-1 alpha (IL1α) is a cytokine member of the interleukin-1 family. IL-1 consists of two distinct forms: IL1α and IL1β that recognize the same cell surface receptors but are distinct proteins with approximately 25% amino acid sequence identity. IL1α is constitutively produced by epithelial cells and plays an essential role in maintenance of skin barrier function. Upon stimulation, a wide variety of cells including osteoblasts, monocytes, macrophages can be induced to express IL1α. IL1α possesses a wide range of metabolic, physiological, haematopoietic activities, and is critically involved in the regulation of the immune responses and inflammatory responses.
|
实验操作视频
新品推荐
Recombinant Human IL-6 Protein (Fc Tag)
Recombinant Mouse BCR protein (His tag)
Recombinant Mouse IL6 protein(His tag)
Recombinant Rat IL2/IL-2/Interleukin-2 protein (His tag)
Recombinant SARS-CoV-2 Nucleocapsid Protein (His Tag)
Recombinant Human Fyn protein(His tag)
Recombinant Mouse CD96/TACTILE protein (His tag)
