Recombinant Human IL-1R8/IL1RAPL1 Protein (Fc Tag)
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- 表达系统： HEK293 Cells
- 蛋白编码： Q9NZN1
| 别称 |
Interleukin-1 Receptor Accessory Protein-Like 1;IL-1-RAPL-1;IL-1RAPL-1;IL1RAPL-1;Oligophrenin-4;Three Immunoglobulin Domain-Containing IL-1 Receptor-Related 2;TIGIRR-2;X-Linked Interleukin-1 Receptor Accessory Protein-Like 1;IL1RAPL1;OPHN4
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| 表达系统 |
HEK293 Cells
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| 序列 |
Leu19-Thr357
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| 蛋白编码 |
Q9NZN1
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| 种属 |
Human
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| 计算分子量 |
68.0 kDa
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| 表观分子量 |
80-100 kDa
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| 标签 |
C-Fc
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| 纯度 |
> 95 % as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
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| 保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
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| 运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
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| 制剂 |
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| 复溶方法 |
Please refer to the printed manual for detailed information.
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| 背景 |
Interleukin-1 receptor accessory protein-like 1; also known as IL1RAPL1; can be detected at low levels in heart; skeletal muscle; ovary; skin; amygdala; caudate nucleus; corpus callosum; hippocampus; substantia nigra and thalamus. IL1RAPL1 functions as a homodimer; it interacts with NCS1; PTPRD. This interaction is PTPRD-splicing-dependent and induces pre- and post-synaptic differentiation of neurons and is required for IL1RAPL1-mediated synapse formation. During dendritic spine formation; it can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans-synaptically binding to PTPRD.
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实验操作视频
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