Recombinant Human IMPA2/IMPase 2 Protein (His Tag)
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- 表达系统： E.coli
- 蛋白编码： O14732
| 别称 |
Inositol Monophosphatase 2;IMP 2;IMPase 2;Inositol-1(or 4)-Monophosphatase 2;Myo-Inositol Monophosphatase A2;IMPA2;IMP.18P
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| 表达系统 |
E.coli
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| 序列 |
Met 1-Lys288
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| 蛋白编码 |
O14732
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| 种属 |
Human
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| 计算分子量 |
33.5 kDa
|
| 表观分子量 |
30 kDa
|
| 标签 |
N-His
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| 纯度 |
> 95 % as determined by reducing SDS-PAGE.
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| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
|
| 保存条件 |
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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| 运输条件 |
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
|
| 制剂 |
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 2mM DTT, pH 8.0.
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| 复溶方法 |
Not Applicable
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| 背景 |
Inositol monophosphatase 2, also known as Inositol-1(or 4)-monophosphatase 2, Myo-inositol monophosphatase A2 and IMPA2, is an enzyme which belongs to the inositol monophosphatase family. IMPA2 catalyzes the dephosphoylration of inositol monophosphate with cofactor Magnesium and Inhibited by high Li+ and restricted Mg2+ concentrations. IMPA2 plays an important role in phosphatidylinositol signaling. IMPA2 can use the myo-inositol monophosphates, scylloinositol 1,4-diphosphate, glucose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. IMPA2 is a pharmacological target for lithium Li(+) action in brain, it is considered to have a role in schizophrenia and bipolar disorder.
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实验操作视频
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