Recombinant Human LSM1 Protein (His Tag)
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- 表达系统: E.coli
- 蛋白编码: O15116
别称 |
U6 snRNA-Associated Sm-Like Protein LSm1;Cancer-Associated Sm-Like;Small Nuclear Ribonuclear CaSm;LSM1;CASM
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表达系统 |
E.coli
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序列 |
Met 1-Tyr133
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蛋白编码 |
O15116
|
种属 |
Human
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计算分子量 |
16.2 kDa
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表观分子量 |
19 kDa
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标签 |
C-His
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纯度 |
> 90 % as determined by reducing SDS-PAGE.
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内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
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保存条件 |
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
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运输条件 |
This product is provided as lyophilized powder which is shipped with ice packs.
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制剂 |
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
复溶方法 |
Please refer to the printed manual for detailed information.
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背景 |
U6 snRNA-Associated Sm-Like Protein LSm1 (LSM1) belongs to the snRNP Sm proteins family. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which plays an important role in pre-mRNA splicing. LSM1 binds specifically to the 3-terminal U-tract of U6snRNA. LSM1 can interact with SLBP when histone mRNA is being rapidly degraded during the S phase. In addition, LSM1 is associated with cellular transformation and the progression of several malignancies including mesothelioma, lung cancer and breast cancer.
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实验操作视频
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