Recombinant Human P4HB Protein (His Tag)
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- 表达系统： HEK293 Cells
- 蛋白编码： P07237
| 别称 |
DSI;ERBA2L;GIT;P4Hbeta;PDI;PDIA1;PHDB;PO4DB;PO4HB;PROHB;Protein Disulfide-Isomerase;PDI;Cellular Thyroid Hormone-Binding Protein;Prolyl 4-Hydroxylase Subunit Beta;p55
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| 表达系统 |
HEK293 Cells
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| 序列 |
Asp18-Lys505
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| 蛋白编码 |
P07237
|
| 种属 |
Human
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| 计算分子量 |
55.9 kDa
|
| 表观分子量 |
65 kDa
|
| 标签 |
C-His
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| 纯度 |
> 95 % as determined by reducing SDS-PAGE.
|
| 内毒素 |
< 1.0 EU per μg of the protein as determined by the LAL method.
|
| 保存条件 |
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
|
| 运输条件 |
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
|
| 制剂 |
Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
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| 复溶方法 |
Not Applicable
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| 背景 |
Protein Disulfide-Isomerase (P4HB) is an endoplasmic reticulum lumen protein that belongs to the protein disulfide isomerase family. P4HB contains two thioredoxin domains and catalyzes the formation, breakage, and rearrangement of -S-S- bonds in proteins. P4HB is involved in hydroxylation of prolyl residues in preprocollagen. P4HB has the ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner. P4HB plays a role in both the influx and efflux of S-nitrosothiol-bound nitric oxide.
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实验操作视频
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